G6PD deficiency is an inborn error of metabolism that predisposes to red blood cell breakdown. What does that mean in English? It means that this is a genetic mutation that, when triggered, can result in your red blood cells breaking down or “blowing up”. Notice I said “when triggered” Most of those who have a G6PD deficiency have NO SYMPTOMS and often never do.  This deficiency most often occurs in males more than females and typically those of Mediterranean, Asian or African decent. It is important to note that this IS NOT A food allergy. This condition was found to be strongly protective against malaria. 

What can cause a “trigger” for one to have symptoms?

There are environmental stressors such as stress; there are also some medications or foods that can also cause trigger an episode/crisis as well as infections. 

What foods or medications can trigger an episode or crisis? 

Foods such as falafel and fava beans (aka. Broad beans) have been found to trigger a crisis. Medications that have been found to trigger an episode have been primaquine, quinines, aspirin, high doses of vitamin C and antimalarial medications. One other thing found to trigger a response, oddly, is moth balls. 

What are symptoms of an episode or crisis?

Some of the symptoms that can been seen with an G6PD crisis would be jaundice (yellow skin), shortness of breath, dark urine and fatigue. If you have a G6PD deficiency and have these symptoms you should seek out immediate medical attention.